Book Chapters
Peer-reviewed Journal Publications
- Multi-task Adaptive Resolution Network for Lymph Node Metastasis Diagnosis from Whole Slide Images of Colorectal Cancer.
Tong Wang, Su-Jin Shin, Mingkang Wang, Qi Xu, Guiyang Jiang, Fengyu Cong, Jeonghyun Kang and Hongming Xu#.
Accepted by IEEE Journal of Biomedical and Health Informatics (JBHI), 2024 (2023 IF: 6.6)(中科院1区-Top)
- Ranking attention multiple instance learning for lymph node metastasis prediction on multicenter cervical cancer MRI.
Shan Jin, Hongming Xu#, Yue Dong, Xiaofeng Wang, Xinyu Hao, Fengying Qin, Ranran Wang, and Fengyu Cong.
Journal of Applied Clinical Medical Physics. e14547, 2024 (2023 IF: 2.0)
- Prediction of lymph node metastasis in operable cervical cancer using clinical parameters and deep learning with MRI data: a multicentre study.
Qin, Fengying, Xinyan Sun, Mingke Tian, Shan Jin, Jian Yu, Jing Song, Feng Wen, Hongming Xu, Tao Yu, and Yue Dong.
Insights into Imaging. vo.15, no.1, pp.1-14, 2024. (2022 IF: 4.7) (中科院2区)
- Predicting pathological complete response based on weakly and semi-supervised joint learning in breast cancer multi-parametric MRI.
Xinyu Hao, Hongming Xu#, Nannan Zhao, Tao Yu, Timo Hamalainenc, and Fengyu Cong
Biomedical Signal Processing and Control (BSPC), 93 (2024): 106164. (2022 IF: 5.1) (中科院2区)
- Simultaneously segmenting and classifying cell nuclei by using
multi-task learning in multiplex immunohistochemical tissue microarray sections.
Ranran Wang, Yusong Qiu, Xinyu Hao, Shan Jin, Junxiu Gao, Heng Qi, Qi Xu, Yong Zhang#, and Hongming Xu#
Biomedical Signal Processing and Control (BSPC), 93 (2024): 106143. (2022 IF: 5.1) (中科院2区)
- Interpretable Sleep Stage Classification Based on Layer-wise Relevance Propagation.
Dongdong Zhou, Qi Xu, Jiacheng Zhang, Lei Wu, Hongming Xu, Lauri Kettunen, Zheng Chang, Qiang Zhang, Fengyu Cong
Accepted at IEEE Transactions on Instrumentation and Measurement. Jan 2024 (2022 IF: 5.6) (中科院2区)
- MIHIC: A multiplex IHC histopathological image classification dataset for lung cancer immune microenvironment quantification.
Ranran Wang, Yusong Qiu, Tong Wang, Mingkang Wang, Shan Jin, Fengyu Cong, Yong Zhang#, Hongming Xu#.
Frontiers in Immunology. 15 (2024): 1334348. (2022 IF: 7.3) (中科院2区)
- The value of multiparametric MRI combined with clinical prognostic parameters in predicting the 5-year survival of stage IIIC1 cervical squamous cell carcinoma.
Qin, Fengying, Huiting Pang, Jintao Ma, Hongming Xu, Tao Yu, Yahong Luo, and Yue Dong.
European Journal of Radiology, pp.111181. 2023 (2022 IF: 3.3)
- Invasion Depth Estimation of Carcinoma Cells using Adaptive Stain Normalization to Improve Epidermis Segmentation Accuracy
Md. Ziaul Hoque, Anja Keskinarkaus, Pia Nyberg, Hongming Xu, and Tapio Seppänena
Computerized Medical Imaging and Graphcs (CMIG), vol.108, pp.102276 2023 (2022 IF: 5.7)(中科院2区)
- Vision Transformers for Computational Histopathology
Hongming Xu, Qi Xu, Fengyu Cong, Jeonghyun Kang, Chu Han, Zaiyi Liu, Anant Madabhushi and Cheng Lu
IEEE Reviews in Biomedical Engineering (RBME), vol.17, pp.63-79, 2024 (2022 IF: 17.6)(中科院1区-Top)
- Machine learning models for predicting adverse pregnancy outcomes in pregnant women with
systemic lupus erythematosous
Xinyu Hao, Dongying Zheng, Muhanmmad Khan, Lixia Wang, Timo Hamalainen, Fengyu Cong, Hongming Xu#, and Kedong Song#
Diagnostics 13, no. 4 (2023): 612. (2022 IF: 3.6)
- Automatic cervical cancer segmentation in multimodal MRI using an EfficientNet encoder in UNet++ architecture
Shan Jin Hongming Xu#, Yue Dong, Xinyu Hao, Fengying Qin, Qi Xu, Yong Zhu, and Fengyu Cong
International Journal of Imaging Systems and Technology, vol.33, pp.362-377, 2023 (2022 IF: 3.3)
- Alleviating Class Imbalance Problem in Automatic Sleep Stage Classification
Dongdong zhou, Qi Xu, Jian Wang, Hongming Xu, Lauri Kettunen, Zheng Chang, and Fengyu Cong
IEEE Transactions on Instrumentation & Measurement, vol.71, pp.1-12, 2022 (2022 IF: 5.6)(中科院2区)
- Spatial heterogeneity and organization of tumor mutation
burden with immune infiltrates within tumors based on whole slide images correlated with patient survival in bladder cancer
Hongming Xu, Sunho Park, Jean R. Clemenceau, Jinhwan Choi, Sung Hak Lee, and Tae Hyun Hwang
Journal of Pathology Informatics, vol.13, pp.100105, 2022
- Spatial analysis of tumor infiltrating lymphocytes in histological sections using deep learning techniques predicts progression-free survival in colorectal carcinoma
Hongming Xu, Yoon Jin Cha, Jean R. Clemenceau, Jinhwan Choi, Sung Hak Lee, Jeonghyun Kang, and Tae Hyun Hwang
The Journal of Pathology: Clinical Research, vol.8, no.4, pp.327-339, 2022 (2021 IF: 4.373)(中科院病理学1区-Top)
- An Unsupervised Method for Histological Image Segmentation based on Tissue Cluster Level Graph Cut
Hongming Xu, Lina Liu, Xiujuan Lei, Mrinal Mandal and Cheng Lu
Computerized Medical Imaging and Graphics, vol.93, pp.101974 August 2021 (2021 IF: 7.422)(中科院2区)
- Machine Learning and Artificial Intelligence–driven Spatial Analysis of the Tumor Immune Microenvironment in Pathology Slides
Hongming Xu, Fengyu Cong and Tae Hyun Hwang
European Urology Focus,vol.7, no.4, pp.706-709 published in August 2021 (2021 IF: 5.952)
Invited Mini-Review Paper (中科院1区-Top)
- Radiomics Features of F-fluorodeoxyglucose Positron-Emission Tomography as a Novel Prognostic Signature in Colorectal Cancer
Jeonghyun Kang, Jae-hoon Lee, Hye-Sun Lee, Eun-Suk Cho, Eun Jung Park, Seung Hyuk Baik, Kang Young Lee, Chihyun Park, Yunku Yeu, Jean Clemenceau,
Sunho Park, Hongming Xu, Changjin Hong and Tae Hyun Hwang
Cancers,vol.13, no.3, pp.392 2021 (IF: 6.636)(中科院2区)
- Computerized classification of prostate cancer Gleason scores from whole slide images
Hongming Xu, Sunho Park and Tae Hyun Hwang
IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB), vol.17, no.6, pp.1871-1882, 2020 (IF: 3.371) [Code Link]
Recommended to be published as the top-3 oral papers in BioKDD workshop 2018, (CCF-B)
- Novel lymph node segmentation and proliferation index measurement for skin melanoma biopsy images
Salah Alheejaw, Hongming Xu, Richard Berendt, Naresh Jha and Mrinal Mandal
Computerized Medical Imaging and Graphics (CMIG), vol. 73, pp. 19-29, 2019 (IF: 4.79)(中科院2区)
- Automated analysis and classification of melanocytic tumor on skin whole slide images
Hongming Xu, Cheng Lu, Richard Berendt, Naresh Jha and Mrinal Mandal
Computerized Medical Imaging and Graphics (CMIG), vol. 66, pp. 124-134, 2018 (IF: 4.79)(中科院2区) [Code Link]
- Automatic nuclear segmentation using multi-scale radial line scanning with dynamic programming
Hongming Xu, Cheng Lu, Richard Berendt, Naresh Jha and Mrinal Mandal
IEEE Transactions on Biomedical Engineering (TBME), vol. 64, no. 10, pp. 2475-2485, 2017 (IF: 4.538)(中科院2区) [Code Link]
- Automatic nuclei detection based on generalized Laplacian of Gaussian Filters
Hongming Xu, Cheng Lu, Richard Berendt, Naresh Jha and Mrinal Mandal,
IEEE Journal of Biomedical and Health Informatics (JBHI), vol. 21, no. 3, pp. 826-837, 2017 (IF: 5.772)(中科院1区-Top) [Code Link]
- Automatic measurement of melanoma depth of invasion in skin histopathological images
Hongming Xu, Richard Berendt, Naresh Jha and Mrinal Mandal
Micron, vol. 97, pp. 56-67, 2017 (IF: 2.251)
- Multi-pass adaptive voting for nuclei detection in histopathological Images
Cheng Lu, Hongming Xu, Jun Xu, Hannah Gilmore, Mrinal Mandal and Anant Madabhushi
Scientific Reports, vol. 6, sp. 33985, 2016 (IF: 4.379)
- Epidermis segmentation in skin histopathological images based on thickness measurement and k-means algorithm
Hongming Xu and Mrinal Mandal
EURASIP Journal on Image and Video Processing, vol. 2015, no. 1, pp. 1-14, 2015 (IF: 1.789) [Code Link]
- An eficient technique for nuclei segmentation based on
ellipse descriptor analysis and improved seed detection algorithm
Hongming Xu, Cheng Lu and Mrinal Mandal
IEEE Journal of Biomedical and Health Informatics (JBHI), vol. 18, no. 5, pp. 1729-1741, 2014 (IF: 5.772) (中科院1区-Top)[Code Link]
Peer-reviewed Conference Proceeding Publications
- Double-tier Attention based Multi-label Learning Network for Predicting Biomarkers from Whole Slide Images of Breast Cancer
Mingkang Wang, Tong Wang, Fengyu Cong, Cheng Lu* and Hongming Xu*
Accepted in International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI), pp. xx, 2024 (CCF-B,医学图像处理顶会)
- Benchmarking Deep Learning Models for Zebrafish Ventricle Segmentation
Yali Wang, Haochun Shi, Xingye Qiao, Mingkang Wang, Fengyu Cong, Yanbin Zhao and Hongming Xu*
In 4th International Conference on Image, Vision and Intelligent Systems, pp. xx, 2024
- Comparative Validation of Graph Neural Networks for Glioma Grading in Whole Slide Images
Qiao Chen, Hongming Xu*, Huamin Qin, Xinyu Hao, Shan Jin, Timo Hämäläinen and Fengyu Cong
In 4th International Conference on Image, Vision and Intelligent Systems, pp. xx, 2024
- Towards efficient deep spiking neural networks construction with spiking activity based pruning
Yaxin Li, Qi Xu, Jiangrong Shen, Hongming Xu, Long Chen, and Gang Pan
Accepted in International Conference on Machine Learning (ICML), pp. xx, 2024 (CCF-A)
- Dual-stream Context-aware Neural Network for Survival Prediction from Whole Slide Images
Junxiu Gao, Shan Jin, Ranran Wang, Mingkang Wang, Tong Wang and Hongming Xu*
In Chinese Conference on Pattern Recognition and Computer Vision (PRCV), pp.3-14, 2023 (CCF-C, Acceptance rate: 37.95%)
- Self-supervised contrastive pre-training integrated with multi-level co-attention for survival prognosis from whole slide images
Junxiu Gao, Xinyu Hao, Shan Jin and Hongming Xu*
In 3rd International Conference on Image, Vision and Intelligent Systems, pp. 650-658, 2023
- Predicting pathological complete response based on weakly and semi-supervised joint learning from breast cancer MRI
Xinyu Hao, Hongming Xu*, Zhao Nannan, Yu Tao, Hamalainen Timo, and Fengyu Cong
In 45th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 1-4, 2023
- SRSA-Net: Separable ResUnit and Self-Attention optimized network for simultaneous nuclei segmentation and classification in histology images
Ranran Wang, Yusong Qiu, Yong Zhang and Hongming Xu*
In Asian-Pacific Conference on Medical and Biological Engineering, pp. 105-112, 2023
- Multiple instance learning for lymph node metastasis prediction from cervical cancer MRI
Shan Jin, Hongming Xu*, Yue Dong, Xinyu Hao, Fengying Qin, Ranran Wang and Fengyu Cong
In 20th IEEE International Symposium on Biomedical Imaging (ISBI), pp. 1-4, 2023
- Statistical Local Binary Patterns (SLBP): application to prostate
cancer Gleason score prediction from whole slide pathology images
Hongming Xu and Tae Hyun Hwang
In 16th IEEE International Symposium on Biomedical Imaging (ISBI), pp. 895-899, 2019
- Automated detection of cavernous malformations in Brain MRI images
Huiquan Wang, S. Nizam Ahmed, Hongming Xu and Mrinal Mandal
In 8th International IEEE EMBS Conference on Neural Engineering,pp.17-20, 2017
- Computerized measurement of melanoma depth of invasion in skin biopsy images
Hongming Xu, Huiquan Wang, Richard Berendt, Naresh Jha and Mrinal Mandal
In 2017 International Conference on Biomedical and Health Informatics (BHI), pp. 17-20, 2017
Acceptance Rate: 38%
- Automated nuclear segmentation in skin histopathological images using multi-scale radial line scanning
Hongming Xu, Huiquan Wang, Richard Berendt, Naresh Jha and Mrinal Mandal
In IEEE-NIH Special Topics Conference on Healthcare Innovations and Point-of-Care Technologies, pp. 175-178, 2016
- Computer aided detection of cavernous malformation in T2-weighted brain MR images
Huiquan Wang, Hongming Xu, S.Nizam Ahmed and Mrinal Mandal,
In IEEE-NIH Special Topics Conference on Healthcare Innovations and Point-of-Care Technologies, pp. 101–104, 2016
- Eficient segmentation of skin epidermis in whole slide histopathological images
Hongming Xu and Mrinal Mandal
In Proceedings of 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 3869-3872, 2015
- Automated segmentation of regions of interest in whole slide skin histopathological images
Hongming Xu, Cheng Lu and Mrinal Mandal
In Proceedings of 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 3855-3858, 2015
Peer-reviewed Workshop Publications
- Spatial analysis of tumor infiltrating lymphocytes based on deep learning using histopathology image to predict progression-free survival in colorectal cancer
Hongming Xu, Yoon Jin Cha, Jean R. Clemenceau, Jinhwan Choi, Sung Hak Lee, Jeonghyun Kang, and Tae Hyun Hwang Tae Hyun Hwang
American Association for Cancer Research Annual Meeting (AACR), April 2022
The abstract is selected as the Oral Presentation in the meeting!
- Transfer learning for tumor mutation burden prediction and spatial heterogeneity analysis from histopathology slides in bladder cancer
Hongming Xu, Sung Hak Lee and Tae Hyun Hwang
American Association for Cancer Research Annual Meeting (AACR), June 2020
- Deep learning can predict microsatellite instability from histology in colorectal cancer across different ethnic groups
Isaiah S. Pressman, Hongming Xu, Jeonghyun Kang, Yoon Jin Cha, Sung Hak Lee and Tae Hyun Hwang
American Association for Cancer Research Annual Meeting (AACR), June 2020
- Deep Gaussian processes for weakly supervised learning: tumor mutation burden (TMB) prediction
Sunho Park, Saehoon Kim, Hongming Xu and Tae Hyun Hwang
Bayesian Deep Learning NeurIPS 2019 Workshop, Dec 2019
- Automatic classification of prostate cancer Gleason scores from digitized whole slide tissue biopsies
Hongming Xu, Sunho Park and Tae Hyun Hwang
In 17th International Workshop on Data Mining in Bioinformatics (BioKDD), August, 2018
The top-3 oral presentations in BioKDD and poster award, and poster presentation in KDD 2018
- Using transfer learning on whole slide images to predict tumor mutational burden in bladder cancer patients
Hongming Xu, Sunho Park, Sung Hak Lee and Tae Hyun Hwang
In 5th Digital Pathology AI Congress: USA, June 2019
- Machine learning for classification of prostate cancer Gleason scores from digitized whole slide tissue biopsies
Hongming Xu and Tae Hyun Hwang
In 38th Annual Cleveland Clinic Research Day, Sep 2018
- Novel lymph node segmentation for skin cancer biopsy images
Salah Alheejawi, Hongming Xu, Richard Berendt, Naresh Jha and Mrinal Mandal
In Proceedings of BHI-2018 International Conference on Biomedical and Health Informatics (BHI), Mar 2018
- Automated diagnosis of melanoma from skin biopsy images
Hongming Xu, Richard Berendt, Naresh Jha and Mrinal Mandal
In Proceedings of BHI-2017 International Conference on Biomedical and Health Informatics (BHI), Feb 2017
- Robust segmentation of regions of interest in skin histopathological images
Hongming Xu and Mrinal Mandal,
The 6th Annual Graduate Research Symposium, University of Alberta, June 2015
Oral Presentation
- A novel technique for nuclei segmentation in skin histopathological images
Hongming Xu and Mrinal Mandal,
The 5th Annual Graduate Research Symposium, University of Alberta, June 2014