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Book Chapters

  1. Deep learning based histopathological image analysis for automated detection and staging of melanoma
    Salah Alheejawi, Mrinal Mandal, Hongming Xu, Cheng Lu, Richard Berendt and Naresh Jha
    Book Chapter in Deep Learning Techniques for Biomedical and Health Informatics, pp. 237-265, Chapter 10, Springer, 2020

Peer-reviewed Journal Publications

  1. Prediction of lymph node metastasis in operable cervical cancer using clinical parameters and deep learning with MRI data: a multicentre study.
    Qin, Fengying, Xinyan Sun, Mingke Tian, Shan Jin, Jian Yu, Jing Song, Feng Wen, Hongming Xu, Tao Yu, and Yue Dong.
    Insights into Imaging. vo.15, no.1, pp.1-14, 2024. (2022 IF: 4.7) (中科院2区)
  2. Predicting pathological complete response based on weakly and semi-supervised joint learning in breast cancer multi-parametric MRI.
    Xinyu Hao, Hongming Xu#, Nannan Zhao, Tao Yu, Timo Hamalainenc, and Fengyu Cong
    Accepted at Biomedical Signal Processing and Control (BSPC). Feb 2024 (2022 IF: 5.1) (中科院2区)
  3. Simultaneously segmenting and classifying cell nuclei by using multi-task learning in multiplex immunohistochemical tissue microarray sections.
    Ranran Wang, Yusong Qiu, Xinyu Hao, Shan Jin, Junxiu Gao, Heng Qi, Qi Xu, Yong Zhang#, and Hongming Xu#
    Accepted at Biomedical Signal Processing and Control (BSPC). Feb 2024 (2022 IF: 5.1) (中科院2区)
  4. Interpretable Sleep Stage Classification Based on Layer-wise Relevance Propagation.
    Dongdong Zhou, Qi Xu, Jiacheng Zhang, Lei Wu, Hongming Xu, Lauri Kettunen, Zheng Chang, Qiang Zhang, Fengyu Cong
    Accepted at IEEE Transactions on Instrumentation and Measurement. Jan 2024 (2022 IF: 5.6) (中科院2区)
  5. MIHIC: A multiplex IHC histopathological image classification dataset for lung cancer immune microenvironment quantification.
    Ranran Wang, Yusong Qiu, Tong Wang, Mingkang Wang, Shan Jin, Fengyu Cong, Yong Zhang#, Hongming Xu#.
    Accepted at Frontiers in Immunology. Jan 2024 (2022 IF: 7.3) (中科院2区)
  6. The value of multiparametric MRI combined with clinical prognostic parameters in predicting the 5-year survival of stage IIIC1 cervical squamous cell carcinoma.
    Qin, Fengying, Huiting Pang, Jintao Ma, Hongming Xu, Tao Yu, Yahong Luo, and Yue Dong.
    European Journal of Radiology, pp.111181. 2023 (2022 IF: 3.3)
  7. Invasion Depth Estimation of Carcinoma Cells using Adaptive Stain Normalization to Improve Epidermis Segmentation Accuracy
    Md. Ziaul Hoque, Anja Keskinarkaus, Pia Nyberg, Hongming Xu, and Tapio Seppänena
    Computerized Medical Imaging and Graphcs (CMIG), vol.108, pp.102276 2023 (2022 IF: 5.7)(中科院2区)
  8. Vision Transformers for Computational Histopathology
    Hongming Xu, Qi Xu, Fengyu Cong, Jeonghyun Kang, Chu Han, Zaiyi Liu, Anant Madabhushi and Cheng Lu
    IEEE Reviews in Biomedical Engineering (RBME), vol.17, pp.63-79, 2024 (2022 IF: 17.6)(中科院1区-Top)
  9. Machine learning models for predicting adverse pregnancy outcomes in pregnant women with systemic lupus erythematosous
    Xinyu Hao, Dongying Zheng, Muhanmmad Khan, Lixia Wang, Timo Hamalainen, Fengyu Cong, Hongming Xu#, and Kedong Song#
    Diagnostics 13, no. 4 (2023): 612. (2022 IF: 3.6)
  10. Automatic cervical cancer segmentation in multimodal MRI using an EfficientNet encoder in UNet++ architecture
    Shan Jin Hongming Xu#, Yue Dong, Xinyu Hao, Fengying Qin, Qi Xu, Yong Zhu, and Fengyu Cong
    International Journal of Imaging Systems and Technology, vol.33, pp.362-377, 2023 (2022 IF: 3.3)
  11. Alleviating Class Imbalance Problem in Automatic Sleep Stage Classification
    Dongdong zhou, Qi Xu, Jian Wang, Hongming Xu, Lauri Kettunen, Zheng Chang, and Fengyu Cong
    IEEE Transactions on Instrumentation & Measurement, vol.71, pp.1-12, 2022 (2022 IF: 5.6)(中科院2区)
  12. Spatial heterogeneity and organization of tumor mutation burden with immune infiltrates within tumors based on whole slide images correlated with patient survival in bladder cancer
    Hongming Xu, Sunho Park, Jean R. Clemenceau, Jinhwan Choi, Sung Hak Lee, and Tae Hyun Hwang
    Journal of Pathology Informatics, vol.13, pp.100105, 2022
  13. Spatial analysis of tumor infiltrating lymphocytes in histological sections using deep learning techniques predicts progression-free survival in colorectal carcinoma
    Hongming Xu, Yoon Jin Cha, Jean R. Clemenceau, Jinhwan Choi, Sung Hak Lee, Jeonghyun Kang, and Tae Hyun Hwang
    The Journal of Pathology: Clinical Research, vol.8, no.4, pp.327-339, 2022 (2021 IF: 4.373)(中科院病理学1区-Top)
  14. An Unsupervised Method for Histological Image Segmentation based on Tissue Cluster Level Graph Cut
    Hongming Xu, Lina Liu, Xiujuan Lei, Mrinal Mandal and Cheng Lu
    Computerized Medical Imaging and Graphics, vol.93, pp.101974 August 2021 (2021 IF: 7.422)(中科院2区)
  15. Machine Learning and Artificial Intelligence–driven Spatial Analysis of the Tumor Immune Microenvironment in Pathology Slides
    Hongming Xu, Fengyu Cong and Tae Hyun Hwang
    European Urology Focus,vol.7, no.4, pp.706-709 published in August 2021 (2021 IF: 5.952)
    Invited Mini-Review Paper (中科院1区-Top)
  16. Radiomics Features of F-fluorodeoxyglucose Positron-Emission Tomography as a Novel Prognostic Signature in Colorectal Cancer
    Jeonghyun Kang, Jae-hoon Lee, Hye-Sun Lee, Eun-Suk Cho, Eun Jung Park, Seung Hyuk Baik, Kang Young Lee, Chihyun Park, Yunku Yeu, Jean Clemenceau, Sunho Park, Hongming Xu, Changjin Hong and Tae Hyun Hwang
    Cancers,vol.13, no.3, pp.392 2021 (IF: 6.636)(中科院2区)
  17. Computerized classification of prostate cancer Gleason scores from whole slide images
    Hongming Xu, Sunho Park and Tae Hyun Hwang
    IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB), vol.17, no.6, pp.1871-1882, 2020 (IF: 3.371) [Code Link]
    Recommended to be published as the top-3 oral papers in BioKDD workshop 2018, (CCF-B)
  18. Novel lymph node segmentation and proliferation index measurement for skin melanoma biopsy images
    Salah Alheejaw, Hongming Xu, Richard Berendt, Naresh Jha and Mrinal Mandal
    Computerized Medical Imaging and Graphics (CMIG), vol. 73, pp. 19-29, 2019 (IF: 4.79)(中科院2区)
  19. Automated analysis and classification of melanocytic tumor on skin whole slide images
    Hongming Xu, Cheng Lu, Richard Berendt, Naresh Jha and Mrinal Mandal
    Computerized Medical Imaging and Graphics (CMIG), vol. 66, pp. 124-134, 2018 (IF: 4.79)(中科院2区) [Code Link]
  20. Automatic nuclear segmentation using multi-scale radial line scanning with dynamic programming
    Hongming Xu, Cheng Lu, Richard Berendt, Naresh Jha and Mrinal Mandal
    IEEE Transactions on Biomedical Engineering (TBME), vol. 64, no. 10, pp. 2475-2485, 2017 (IF: 4.538)(中科院2区) [Code Link]
  21. Automatic nuclei detection based on generalized Laplacian of Gaussian Filters
    Hongming Xu, Cheng Lu, Richard Berendt, Naresh Jha and Mrinal Mandal,
    IEEE Journal of Biomedical and Health Informatics (JBHI), vol. 21, no. 3, pp. 826-837, 2017 (IF: 5.772)(中科院1区-Top) [Code Link]
  22. Automatic measurement of melanoma depth of invasion in skin histopathological images
    Hongming Xu, Richard Berendt, Naresh Jha and Mrinal Mandal
    Micron, vol. 97, pp. 56-67, 2017 (IF: 2.251)
  23. Multi-pass adaptive voting for nuclei detection in histopathological Images
    Cheng Lu, Hongming Xu, Jun Xu, Hannah Gilmore, Mrinal Mandal and Anant Madabhushi
    Scientific Reports, vol. 6, sp. 33985, 2016 (IF: 4.379)
  24. Epidermis segmentation in skin histopathological images based on thickness measurement and k-means algorithm
    Hongming Xu and Mrinal Mandal
    EURASIP Journal on Image and Video Processing, vol. 2015, no. 1, pp. 1-14, 2015 (IF: 1.789) [Code Link]
  25. An eficient technique for nuclei segmentation based on ellipse descriptor analysis and improved seed detection algorithm
    Hongming Xu, Cheng Lu and Mrinal Mandal
    IEEE Journal of Biomedical and Health Informatics (JBHI), vol. 18, no. 5, pp. 1729-1741, 2014 (IF: 5.772) (中科院1区-Top)[Code Link]

Peer-reviewed Conference Proceeding Publications

  1. Dual-stream Context-aware Neural Network for Survival Prediction from Whole Slide Images
    Junxiu Gao, Shan Jin, Ranran Wang, Mingkang Wang, Tong Wang and Hongming Xu*
    Accepted in the Chinese Conference on Pattern Recognition and Computer Vision (PRCV), pp. xx, 2023 (CCF-C, Acceptance rate: 37.95%)
  2. Self-supervised contrastive pre-training integrated with multi-level co-attention for survival prognosis from whole slide images
    Junxiu Gao, Xinyu Hao, Shan Jin and Hongming Xu*
    Accepted in the 3rd International Conference on Image, Vision and Intelligent Systems, pp. xx, 2023
  3. Predicting pathological complete response based on weakly and semi-supervised joint learning from breast cancer MRI
    Xinyu Hao, Hongming Xu*, Zhao Nannan, Yu Tao, Hamalainen Timo, and Fengyu Cong
    Accepted in Proceedings of 45th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. xx, 2023
  4. SRSA-Net: Separable ResUnit and Self-Attention optimized network for simultaneous nuclei segmentation and classification in histology images
    Ranran Wang, Yusong Qiu, Yong Zhang and Hongming Xu*
    Accepted in 2023 China Biomedical Engineering Conference & Medical Innovation Summit, pp. xx-xx, 2023
  5. Multiple instance learning for lymph node metastasis prediction from cervical cancer MRI
    Shan Jin, Hongming Xu*, Yue Dong, Xinyu Hao, Fengying Qin, Ranran Wang and Fengyu Cong
    Accepted in 20th IEEE International Symposium on Biomedical Imaging (ISBI), pp. xx-xx, 2023
  6. Statistical Local Binary Patterns (SLBP): application to prostate cancer Gleason score prediction from whole slide pathology images
    Hongming Xu and Tae Hyun Hwang
    In 16th IEEE International Symposium on Biomedical Imaging (ISBI), pp. 895-899, 2019
  7. Automated detection of cavernous malformations in Brain MRI images
    Huiquan Wang, S. Nizam Ahmed, Hongming Xu and Mrinal Mandal
    In 8th International IEEE EMBS Conference on Neural Engineering,pp.17-20, 2017
  8. Computerized measurement of melanoma depth of invasion in skin biopsy images
    Hongming Xu, Huiquan Wang, Richard Berendt, Naresh Jha and Mrinal Mandal
    In 2017 International Conference on Biomedical and Health Informatics (BHI), pp. 17-20, 2017
    Acceptance Rate: 38%
  9. Automated nuclear segmentation in skin histopathological images using multi-scale radial line scanning
    Hongming Xu, Huiquan Wang, Richard Berendt, Naresh Jha and Mrinal Mandal
    In IEEE-NIH Special Topics Conference on Healthcare Innovations and Point-of-Care Technologies, pp. 175-178, 2016
  10. Computer aided detection of cavernous malformation in T2-weighted brain MR images
    Huiquan Wang, Hongming Xu, S.Nizam Ahmed and Mrinal Mandal,
    In IEEE-NIH Special Topics Conference on Healthcare Innovations and Point-of-Care Technologies, pp. 101–104, 2016
  11. Eficient segmentation of skin epidermis in whole slide histopathological images
    Hongming Xu and Mrinal Mandal
    In Proceedings of 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 3869-3872, 2015
  12. Automated segmentation of regions of interest in whole slide skin histopathological images
    Hongming Xu, Cheng Lu and Mrinal Mandal
    In Proceedings of 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 3855-3858, 2015

Peer-reviewed Workshop Publications

  1. Spatial analysis of tumor infiltrating lymphocytes based on deep learning using histopathology image to predict progression-free survival in colorectal cancer
    Hongming Xu, Yoon Jin Cha, Jean R. Clemenceau, Jinhwan Choi, Sung Hak Lee, Jeonghyun Kang, and Tae Hyun Hwang Tae Hyun Hwang
    American Association for Cancer Research Annual Meeting (AACR), April 2022
    The abstract is selected as the Oral Presentation in the meeting!
  2. Transfer learning for tumor mutation burden prediction and spatial heterogeneity analysis from histopathology slides in bladder cancer
    Hongming Xu, Sung Hak Lee and Tae Hyun Hwang
    American Association for Cancer Research Annual Meeting (AACR), June 2020
  3. Deep learning can predict microsatellite instability from histology in colorectal cancer across different ethnic groups
    Isaiah S. Pressman, Hongming Xu, Jeonghyun Kang, Yoon Jin Cha, Sung Hak Lee and Tae Hyun Hwang
    American Association for Cancer Research Annual Meeting (AACR), June 2020
  4. Deep Gaussian processes for weakly supervised learning: tumor mutation burden (TMB) prediction
    Sunho Park, Saehoon Kim, Hongming Xu and Tae Hyun Hwang
    Bayesian Deep Learning NeurIPS 2019 Workshop, Dec 2019
  5. Automatic classification of prostate cancer Gleason scores from digitized whole slide tissue biopsies
    Hongming Xu, Sunho Park and Tae Hyun Hwang
    In 17th International Workshop on Data Mining in Bioinformatics (BioKDD), August, 2018
    The top-3 oral presentations in BioKDD and poster award, and poster presentation in KDD 2018
  6. Using transfer learning on whole slide images to predict tumor mutational burden in bladder cancer patients
    Hongming Xu, Sunho Park, Sung Hak Lee and Tae Hyun Hwang
    In 5th Digital Pathology AI Congress: USA, June 2019
  7. Machine learning for classification of prostate cancer Gleason scores from digitized whole slide tissue biopsies
    Hongming Xu and Tae Hyun Hwang
    In 38th Annual Cleveland Clinic Research Day, Sep 2018
  8. Novel lymph node segmentation for skin cancer biopsy images
    Salah Alheejawi, Hongming Xu, Richard Berendt, Naresh Jha and Mrinal Mandal
    In Proceedings of BHI-2018 International Conference on Biomedical and Health Informatics (BHI), Mar 2018
  9. Automated diagnosis of melanoma from skin biopsy images
    Hongming Xu, Richard Berendt, Naresh Jha and Mrinal Mandal
    In Proceedings of BHI-2017 International Conference on Biomedical and Health Informatics (BHI), Feb 2017
  10. Robust segmentation of regions of interest in skin histopathological images
    Hongming Xu and Mrinal Mandal,
    The 6th Annual Graduate Research Symposium, University of Alberta, June 2015
    Oral Presentation
  11. A novel technique for nuclei segmentation in skin histopathological images
    Hongming Xu and Mrinal Mandal,
    The 5th Annual Graduate Research Symposium, University of Alberta, June 2014

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